RISKFACTORS OF Endometrial adenocarcinoma

Endometrial adenocarcinoma 

Post-menopausal bleeding

Endometrial adenocarcinoma most common type

Gross: poypoid endometrial mass, invasion of myometrium.

RICKFACTORS: 

1.  Early menarche

2.  Late menopause

3.  HTN

4.  DM

5.  Obesity

6.  Chronic anovulation

7.  ESTROGEN => estrogen producing ovarian tumors (granulosa cell tumors)

8.  ESTROGEN => replacement therapy

9.  ESTROGEN => TAMOXIFEN is an estrogen receptor antagonist in breast use to tx breast cancer, BUT has an agonist effect on endometrium, causing endometrial hyperplasia and then cancer.

10.                   Lynch Sd: Hereditary Non-Polyposis colorectal cancer; in women higher risk of not only colon but also endometrial and ovarian cancer

REMEMBER—

CORPUS CARCINOMA SYNDROME=

HOD OF ENDOMETRIUM

1.  HTN

2.  OBESITY

3.  DM

4.  CA ENDO

SIMPSON PAIN=COLICKY PAIN IN CA ENDO

WORST PROGNOSIS

1.  PAPILLARY SEROUS

2.  CLEAR CELL VARIETY