Saturday, 4 January 2014

JIPMER 2012 PAPER

JIPMER 2012 PAPER


 1) Levosimandan - sensiting calcium to tropomyosin.................
 2) supracondylar fracture humerus?????
 median
 3) Waldeyer fascia
 4) antibody a/w IgA nephropathy is against? Cd 71
 gA nephropathy overexpresses 1- cd51 2-cd61 3-cd71 4-cd81
 5) S 100-neuroendocrine

 6) miyagawa body????lgv

 7) primary action of chemoreceptors? a.mild tachycardia, vasodilation b.bradycardia,vasoconstriction c.tachycardia , vasoconstriction d.bradycardia, vasodilation

 8) origin fro ecto and mesoderm??????
 Adrenals?
 9) anal sphincter???? circular


 10) spinothalmic tract?????


 11) ossification at 2 month????lunate scaphoid????? ANS capitate


 12) congenital glaucome?sx?goniotomy?trabaculoplasty? ....

 13) electrical synapse?gap junction ans

 14) norepinphrine acxts by reducing camp in alfa 2recptors?

 15) pop diadvantage?irregular bleed


 16) iodine 131 half life 8 days


 17) non ketotic hypoglycemis a/e galactosemia fructose intolerance hyperinsulinemia??

 18) induseum griseum?
 induseum griseum is a vestige of hippocampal development. supracallosal gyrus (induseum griseum; gyrus epicallosus) consists of a thin layer of grey matter in contact with the dorsal surface of the corpus callosum and continuous laterally with the grey matter of the cingulate gyrus

 19) ‎*flipped LDH isoenzymes occur in: a)myositis b)myocardial infarction c)grave's disease d)?myasthenia gravis
 Ans MI
 20) ‎*55yr old woman had postmenopausal bleeding, she underwent hysterectomy. histopatholgy showed endometrioid type of endometrial carcinoma. what would have led to this type of cancer: a)adenomyosis b)multiparity c)excess estrogens d)??OCPs
 21) ‎*wilm"s tumor gene WT1 is located on chromosome??
 11q 13

 22) ‎*which is a photochromogen: a)mycobacterium gordonae b)mycobacterium kansasii ans c)mycobacterium schleii d)mycobacterium marinum


 23) ‎*thiamine deficiency shows: a)reduced RBC trasketolase b)?


 24) * according to WHO International Health regulations, area around ports and airports free of mosquitoes should be: a) 100metres b)200m c)300m d)400m


 25) *mycobacterium simiae is a: a)photochromogen b)scotochromogen c)rapid-grower d)non-photpchromogen


 26) *ELISA for virulence marker antigen(VMA) is done to detect virulence in : a)atypical mycobacteria b)hemophilus influenzae c)?strptococuus pyogenes
 E coli

 27)type 2 rta a/e lowe cystinuria


 28) thyroid peroxidaSE does a/e release of thyroglobulin into the colloid?


 29) c/i in liver failure? spironolactone?
 Ans carbonic anhydrase inhibitor


 30) iucd a/e?reduces fertility after removal?


 31) estrogen a/e? reduces fsh,secreted by theca causes lh suerge,


 32) theirsch graft?partial thickness


 33) post ethmoid sinus opens into superior meatus!


 34) epoophoran upper part of wolfian duct


 35) uterine axis is at internal os


 36) vpm nucleus of thamlamus?medial lemniscus/lat lemniscus?trigeminal nucleus(ANS)?


 37) g2b/3a?glanzmans?
 Bernard Soulier

 38) a/e are a part of hypopharynx ?post cricoid?pyriform sinus
 Epiglottis

 39) glottic cancer with fixed chords stage 3

 40) recurrent apnea bradycardia and syncope? cong heart block?
 Pertusis

 41) most common nerve involved with ophthalmic, mandibular, ,axillary as d option???????????? V1


 42) eale's disease cause...wat type of blindness ?????????????????????/
 Sudden painless

 43) famciclovir is the prodrug of penciclovor


 44) sagittal suture closure -scaphocephaly.


 45) aliskiren- direct renin inhibitor


 46) hyperchloremic acidosis- ureterosigmoiostomy


 47) *resection of adjacent bowel is usually necessary during resection of: a)chylolymphatic cyst b)enterogenous cyst ANS c)simple cyst d)? mesenteric cyst


 48) *intussusection is caused by; a)submucuos dermoid (ANS) b)subserous dermoid c)?

 49) lyre sign?- glomus tympanicum jugulare acoustic carotid body tumor
 Ans carotid body tumor

 50) gutzman test done in puberphonia

 51) adverse effects of beta blocker a/e bron constriction ,rebound tachy, ortho hypotension,poor response to hypoglycemia
 Ans it is used in ortho hypotension

 52) cerebral salt wasting a/e hypovolemia


 53) hypertonic hyponatremia?mannitol


 54) a/e true abt cystic fibrosis early hyperglycemia,res trac infection common, majority males with infertility, chloride >70meq


 55) mesalamine used for Ulcer colitis alzheimer ? UC

 56) treatment of soft tissue sarcoma ? wide excicion

 57) pinch purpura? primary amyloidosis


 58) amyloid deposits commonly in? renal vessels

 59) Emphysematous cholecystitis caused by- clostridium welchii


 60) Malignant pustule- anthrax

 61) Most common melanoma- supfl spreading


 62) about ear a/e oval window transmits sound to perilymph??


 63) Aortic opening.- at T12


 64) reid index in chronic bronchitis


 65) ochronosis is seen in chronic poisoning wid..?? Carbolic acid


 66) small cell Ca lung..dna of d necrotic cells get deposited on vessels-a]psammoma body b]azzopardy effect c]button collar lesion
 ANS b
 67) lowest court 2 giv imprisonment less den 10 yrs..a]Chief judicial magistrate B] additional session judge C]assistant session judge Dchief metroploitan,,


 68) aconite poisoning not a symptom- hypertension. hypotension is usually seen


 69) Parotid gland is supplied by- a) Otic ganglion


 70) allowed fluoride level in water? <1 .5="" dl="" mg="" p="">

 71) particle size inhaled in lung <5 microns="" p="">

 72) radiation dose absorbed in SI unit Gray


 73) ab. To gm csf ‎, Alveolar proteinosis
 -
 74) socialy learned behaviour??????????????????
 culture is learned behavior which is socialy acquired


 75) icds program under 1 ministry of H & FW 2 MINISTRY OF EDUCATION 3 MINISTRY OF SOCIAL WELFERE 4 MINISTRY OF H R D
 At present Ministry of Women and Child Development which until 2006 was under Ministry of H RD (started when HRD was under Ministry of social justice)

 76) 1-Nephrotic syndrome asso. with-

 a) P. vivax b) p. malariae (ans) c) P. f. d) P. ovale

 77) brunner glands n duodenam


 78) Sreening test correctly define TRUE NEGATIVE 1. SENSITIVITY 2 POSITIVE PREDICTIVE VALUE 3 SPECIFICITY 4 NEGATIVE PREDICTIVE VALUE


 79) Tardive Ulnar palsy: Cubitus varus Cubitus valgus genu valgum genu varum


 80) lead poisoning inorganic which is not a symptom insomnia


 81) time period b/w primary case and secondary case median incubation period serial interval generation time ??


 82) seizure caused by a/e cycloserine, clozapine tramodol propofol
 All increase seizure threshold!!!! Clinically, maybe propofol… J

 83) post anesthesia minitoring? pain ambullation nausea drinking
 Ans ambulation

 84) least elimination half life? propofol thiopentone midazolam


 85) all routes preferred in ? fentanyl


 86) alveolar hge in a/e idiopathic pulmanory fibrosis , pul cpillaritis?


 87) self esteem narcissist

 88) dimorphic? histoplasma


 89) endolymph? Scala media


 90) diarrhoea is sen ? metformin


 91) serum albumin gradien<1 .1="" nephritic="" p="">

 92) all r transudate except? uremia svc syndrome


 93) fatty liver in pregnancy a/e? fatal

 94) turner syndrome?


 95) pri amenorrhea with n karyotype? Mullerian agenesis

 96) x linked a/e rett

 97) most common symptom in fibroadenosis? pain

 [snip]) ant colporraphy with perinnnioraphy?

 99) g6pd deficiency?

 100) hereditary spherocytosis? Spherocytes wikll disappear after splenectomy

 101) hemolytic anemia? Low LDH

 102) sickle cell anemia? Aplastic crisis spleen

 103) oxaluria? glycine

 104) chronic liver disease poor prognosis? inc alfa feto protein
 Inc PT
 105) placental trophoblastic?

 106) partial mole? a/e diploid

 107) hydati mole a/e? cyto trophoblast predominant

 108) c/i in placenta previa a/e speculum exam

 109) ocp protect against al/e ? cervical ca


 110) type 2 muscla fibre?


 111) Zoonotic asso with agricultural workers a/e Dracunculus leptospirosis Qfever ?? Tetanus


 112) MEDIAN NERVE SUPPLY A/E 1 ADDUCTOR POLLICIS BREVIS 2 FLEXOR PLLICIS BREVIS 3 OPPONENS POLIS 4 ABDUCTOR POLLICIS BREVIS

 113) sympathetic vasodilator fibers ?
 a) arises from frontal lobe


 114) decreased basophils in cushings


 115) dehydration in children is due to al/e less basal fluid requirements?


 116) undescenden testis cannot descend after? 4 months , 6, 8 months


 117) glut 5 is fructose transporter. a/e ANS GLUT 2 in neurons (it is GLUT 3)

 118) a/e about phenobarbitone hypoglycemia ?

 119) c/i antiepileptic in child treated with ketogenic diet ? valproate

 120) 4. False about amiodarone? A. Bradycardia and heart block B. Drug of choice for atrial fibrillation C. High incidence of torsa des pointes D. Dose related pulmonary toxicity is the most important adverse effect answer C. Katzung 11th ed, p240-241

 121) 6. Anticraving drug used in alcohol dependence? Answer C. Naltrexone

 122) True about Sporothricosis are all EXCEPT A. Spread along lymphatics B. Drug of choice is Potassium iodide C. Medlar body D. Caused by S.schenckii answer C. Chakraborthy p631

 123) Thayer martin media for? Answer- Neisseria

 124) 12.Streptococcal capsule is made up of? A. Hyaluronic acid B. Polysaccharide C. Polypeptide D...... Answer- A

 125) 13. Streptococcus pyogenes experiment by Griffith is? A. Lysogenic conversion B. Transduction C. Transformation D. Conjugation answer- C. Chakroborthy p79

 126) 14.Contaminant in home canned vegetables and smoked fish? A. Staph B. Cl.botulinum C. Salmonella D. B.cereus answer- B. Harrison17th p901

 127) 15.In Africa Children, which is the most common type of kaposi sarcoma? A. Classical type B. Lymphadenopathic type C. Hodgkin ds D. AIDS asso type answer-B. Wikipedia

 128) 16. Periportal fibrosis caused by? A. S.japonicum B. S.mansoni C. S.hematobium D. S.mekongi answer- A. Paniker p116


 129) 17.Primary amebic encephalitis? Answer- nagleria fowleri

 130) . Chromosomal breakage a/e Duchenne


 131) 19. Guarneri bodies? Answer- pox virus

 132) 21. Number of bacilli per field for diagnosing Hansen's ds is? A. 10 per field B. 10^2 C. 10^3 D. 10^4 Answer- A? Chakraborthy p410

 133) Xeroderma pigmentosa nucleotide excision repair


 134) autonomous hyperplsaia in? fibromatosis


 135) 5.touton giant cells? Xanthomas!


 136) transplacental carcinogenesis? Vaginal adeocarcinoma



 137) which drug dosage should be decreased with concomitant administration of allopurinol mercaptopurine ?? ?? ??


 138) criggler najar syndrome
 Defect in conjugation

 139) Type of lens wit minimum post subcapsular calcification. . A PMMA B Hydrophilic
 acrylic c hydrophobic acrylic (ans?) d crystalline lens


 140) Lesch nyhan syndrome HGPPT


 141) substrate level phosphorylation


 142) classical liver lobule –around central vein


 143) red cells stored in blood bank? Low Na


 144) less total ant pituitary hormone


 145) mech not that gr8 for T cells -phagocytosis

 146) antibiotic act on protein synthesis : erythromycin


 147) T helper 1- CMI


 148) myagalia ??


 149) minimal alveolar conc of anesthetic agent is potency


 150) glycopeptide antibiotic vancomycin


 151) metaplasia from? Stem cells??


 152) neonatal sepsis org Gr D strp (agalactae)


 153) endocopes disinfected with guteraldehyde


 154) weil disease L interrogans

 155) most common world wide zoonotic / brucella anthrax rabies leptospirosis
 ANS brucella

 156) subclavian steal syn ?first part of sub clavian artery blocked


 157) maximum protein binding? morphine fentanyl sulfentan
 Sufentanil

 158) Benefit of screening procedure in? colon cancer


 159) GVHR monitor a/e skin liver lung intestine
 Ans liver

 160) mesangial contraction by? histamine bradykinin,nitric oxide,


 161) specimen required for cytogenetic study in macerated fetus? WBC RBC fibroblast from achilles, fibroblast from skin fascia


 162) early symptom in rectal cancer? constipation, diahorrea n constipation, bleeding, pain


 163) common skeletal manifestation in NF1? sphenoid dysplasia,scoliosis,pseudoarthrosis,thinning of long bones


 164) early symptom in TB hip? loss of joint space,collapsed head, osteopenia


 165) cause for ganglion degenaration of tendon sheath

 166) monteggia fracture...


 167) haemangioblastoma of cerebellum and retina-von hippel landau

 168) kobner phenomenon present n vitiligo,lichev planus,psoriasis not n dermatitis herpetiformis

 169) fatty liver in alc d/t

 170) A/E TRUE ABOUT DELIRIUM 1 NO DIRUNAL VARIATION 2 ACUTE IN ONSET 3 ? 4?



 171) strawberry gum in wegener



 172) herat boarder formed by A/E IN PA View 1 RA 2 RV 3 LV 4 AORTIC ARCH


 173)eyelas infestation with pediculosis capitis pediculosis humanis pthris pubis

 174) KANVAL SIGN IS SEEN IN 1 TENDON SHATHS INFLAMTION 2 ? 3? 4?


 175) during outbreak of an epidemic first thing to do: confirmation of diagnosis confirmation of the epidemic ?? ??


 176) malondialdehyde lipid peroxidation

 177) method in which whole of body organs removed for dissection? virchow ghon
 ANS letulle??

 178) disposal of sharp instruments in which colour bag? Blue/ transparent

 179) which among is saturated fatty acid? Palmitic acid

 180) most essential fatty acid linoliec acid aracadonic acid linolenic acid eicosapentanoic acid


 181) Not true abt mitochondrial diabetes: early hyperglycemia asso with weight gain ??? ??


 182) paranasal sinus not present at birth.i think ans frontal sinus


 183) Miculiz cell & Russel Body seen in 1 Rhinospordiosis 2 Rhinosclerosis 3? 4 ?


 184) a person died of menigooencephalitis. autopsy shows gelainous fluid, cystic spaces, organism has capsule and is round, which stain will it take: Mucicarmine alicial blue giemsa prussian blue


 185) Subclinical infection is seen in JE



 186) osteomalasia x ray finding
 Loosers zone

 187) marketing of a drug after which pahse of drug trial
 1 PHASE 1
 2 PHASE 2
 3 PHASE3 ans
 4 PHASE 4

 188) ‎3 Sign of COA

 189) nephelometry uses light scattering property
 190) regarding Transfusion Associiated Lung Injury FALSE is:
 anti-HLA antibodies
 seen in multiigravid/parous women
 leucocytes in pulmonary circulation
 causes noncardiogenic pul.edema
 All seem to be true

 191) which is not community acquired pneumonia: Acinetobacter baumanii mycopllasma staph areus H.influenzae
 Ans a
 192) which is not an epiigenetic modification: poly A tailing Splicing dna methylation histone acetylation

 193) Pulmonary plethora a/e TAPVC TOF ?? ??


 194) Hypoxemia in Asthma is due to: V/Q mismatch Shunt hypoventilation ??


 195) pH of a soln having 1x10 power -9 Hydrogen ions 12 9 4 3
 Ans9

 196) Vol of fluid to repaced in a 10kg child of obvious dehydration in first 4 hours 500ml 750ANS 1200 1000


 197) Lacunar infarcts a/e: loss of consciousness hemisensory loss clumpsy hand can be seen hemiparesis or??


 198) which is only filtered into renal tubules DTPA DMSA MAG3 EC
 Ans dtpa

 199)Tc Labellled RBC are used for a/e GI bleed LV function ?? ?? Ans hepatoblastoma

 200) how many PERMANENT teeth at 8years............16,20,24
 Ans 12
 201) Radiolucent stones: uric acid cysteine sruvite calcium oxalate
 Ans uric acid >> cysteine
 202) which substance is least lost in urine: albumin haemoglobin myoglobin ??
 Albumin (<150mg hrs="" normally="" p="">
 203) maximum no of oocytes -20 weeks

 204) cranial end of wolffian –epoopharon


 205)true about spastic diplegia upper limbs only hemiparesis of upper an lower limb upper limb>lower limb lower limbs only


 206)according to safe strategy WHO recommends the use of _____ for the control of trachoma azithromycin tetracycline ?? ??


 207) features of achondroplasia a/e: trident hand acro-chondrolysis tombstone iliac bones ??
 Acral osteolysis

 208) non contraceptives use of ocp r all ex-ca cervix

 209) impending uterine rupture a/e;peritoneal pregnancy


 210)Seen in ARDS a/e PaO2:fio2 Ans PCWP<18 p="">
 211)) ultrashort acting neuromuscular blocking agen suxametonium vecuronium
 Ans sux
 212) suxamethonium resistance seen in: mysthenia gravis lambert eaton myasthenic syndrome polymyositiis dermatomyositis or duchenne muscular dysrtrophy or??

 213) false abt ear chorda tympani passes on the inner surface of pars tensa pars flaccide is in between the malleolar folds tympanic membrane makes 55 degree angulation with meatus amplification function is mainly due to lever action of ear ossicles


 214) antibiotics are given in this type of psoriasis guttate pustular impetigo herpetiformis ??


 215) regarding transfusion associated ANAPHYLACTIC reactions False is
 differentr from allergy
 seen in IgG deficient individuals
 washed blood products prevents it
 216) single most important predictor for CAD
 Increased LDL

 217) True about PET scan
 single photon peak at 511 kev
 dual photon peak at 511 kev ans
 10 times more sensitive than gamma cameras
 Lead collimators are used

 218) Rbc protoporphyrin inc in iron def anemia

 219) regarding 'affect' in psychiatric interview not true is:
 it has objective component
 has subjective component
 a cross-sectional manifestation of emotion
 persistant tone of feeling for a period of time ANS This is mood, not affect

 220) drug bound to alpha 1 acid glycoprotein all except
 lignocaine
 disopyramide
 quinidine
 propranolol
 All are basic drugs and hence I expect all to be bound to alpha glyco!
 221)ovarian cause of hirsutism
 a. pcos
 222) Insulin dependent glucose transport occurs in all except
 skeletal muscle
 heart ans
 liver
 adipocytes
 223) fetal bleed: vasa previa

 224) one can increase inspiratory airway pressure by
 decreasing PEEP
 increasing PIP ANS
 decreasing inspiratory:expiratory time ratio
 225) which is not true about indication of exchange transfusion
 1 cord bilirubin> 4mg%
 2 cord hb < 10mg %
 3 rate of bilirubin increase is > 0.5mg%
 4 total bilirubin 10 mg/dL Ans


 226) human milk as compare to cow milk has more
 1 fat
 2 protien
 3 lactose
 4 ?

 227) rmp ca- 130

 228) false regarding bronchiecteasis
 dry type is seen in apices
 mucolytic has proven action in relief of secretions
 antibiotics are indicated during exacerbations

 229) retinal breaks are seen in the following type of retinal degeneration
 snowflake degeneration
 lattice degeneration(ans)

 230) contraindicated in a diabetic
 ray amputation
 symes amputation
 transmetatarsal amputation
 below ankle amputation

 231) migratory thrombophlebitis is not seen in
 ca colon
 ca pancreas
 ca prostate
 ca lung ANS

 232) a patient with prolonged aptt, underwent a surgery without any bleeding
 complication... which factor is deficient
 V ans?
 VII
 XII
 X
 233) Pin index
 234) heparin release- lip lipase

 235) crosses bbb- physostigmine
 236) buspirone a/e sedative

 237) Interstitial nephritis is C/B
 1 methicillin ans
 2 cloxacillin
 3 amoxycillin

 238) Neural cells expt- Ependymal phagocytosis
 239) sertoli cell secrets-
 ans-androgen binding protien

 240) MM- IL 6

 241) 30 years male SUDDEN Backache with right sided radiculopathy IN ABILITY TO PASS URINE ETC..-LUMBAR CANL STENOSIS/CAUDA EQUINA SYN/?

 242) spiramycin toxoplasmosis
 243) Coagulation necrosis: 4 days after MI
 244) venous air embolism during surg seen with
 supine
 sitting ans
 prone
 lateral position

 245) catII TBans-
 defaulter

 246) weaning mode of ventilation a/e Pressure control

 247) LAP decreased in CML

 248) paronyhia best treatment. Partial nail removal/nail removal/ lifting of eponychium
 249) Acute Tubular Necrosis/ SIADH causes eu volumic Hyponatremia

APPG 2012 - ENT Mcqs

APPG 2012  - ENT Mcqs
 1.Merciful anosmia is seen in
 a.Atrophic rhinitis
 b.Allergic rhinitis
 c.Ethmoidal polyposis
 d.Wegener’s granulomatosis

Explanation: Atrophic rhinitis(Ozaena) is a chronic inflammation of nose characterized by atrophy of nasal mucosa and turbinate bones. The nasal cavities are roomy and full of foul smelling crusts. Disease is commonly seen in females and starts around puberty. There is foul smell from the nose making the patient a social outcast though patient himself is unaware of the smell due to marked anosmia (merciful anosmia) which accompanies these degenerative changes.

 2.Acoustic neuroma most commonly arises from
 a.Nervous intermedius
 b.Superior vestibular nerve
 c.Inferior vestibular nerve
 d.Cochlear nerve

 Explanation: The answer was superior vestibular nerve before a few years and now it is Inferior vestibular nerve based on the recent research done.

 3.The surgical procedure currently recommended for ethmoidal polyposis is
 a.Functional endoscopic sinus surgery
 b.Caldwel-Lucs procedure
 c.Sinoscopy
 d.Antral lavage
ans- a
 4.Which surgery is commonly performed for unsafe CSOM?
 a.Myringotomy
 b.Myringoplasty
 c.Modified radical mastoidectomy
 d.None of the above

ans -c
 5.Frisch bacillus causes
 a.Rhinoscleroma
 b.Rhinosporidiosis
 c.Rhinophyma
 d.Lupus vulgaris

Explanation:
 Rhinoscleroma, or simply Scleroma, is a chronic granulomatous bacterial disease of the nose that can sometimes infect the upper respiratory tract.It most commonly affects the nasal cavity—the nose is involved in 95-100 per cent of cases—however, it can also affect the nasopharynx, larynx, trachea, and bronchi. Slightly more females than males are affected and patients are usually 10 to 30 years of age. Rhinoscleroma is considered a tropical disease and is mostly endemic to Africa and Central America, less common in the United States. It is caused by Klebsiella rhinoscleromatis—subspecies of Klebsiella pneumoniae— a gram-negative, encapsulated, nonmotile, rod-shaped bacillus (diplobacillus), member of the Enterobacteriaceae family. It is sometimes referred to as the "Frisch bacillus," named for Anton von Frisch who identified the organism in 1882. It is contracted directly by droplets or by contamination of material that is subsequently inhaled.
 6.Emergency tracheostomy is not indicated in
 a.Acute severe asthma
 b.Foreign body in respiratory tract
 c.Laryngeal cancer producing stridor
 d.Bilateral vocal cord paralysis
ans-a
 7.Labyrinthine artery is a branch of
 a.anterior inferior cerebellar artery
 b.posterior inferior cerebellar artery
 c.middle meningeal artery
 d.basilar artery
Explanation:The labyrinthine artery (auditory artery, internal auditory artery), a long slender branch of the anterior inferior cerebellar artery (85%-100% cases) or basilar artery (15% cases), arises from near the middle of the artery; it accompanies the vestibulocochlear nerve through the internal acoustic meatus, and is distributed to the internal ear.

 8.Cork screw esophagus seen on barium swallow is a feature of
 a.achalasia cardia
 b.diffuse esophageal spasm
 c.nut-cracker esophagus
 d.gastroesophageal reflux
ans-b
 9.The most frequent congenital laryngeal lesion is
 a.laryngomalacia
 b.subglottic hemangioma
 c.congenital subglottic stenosis
 d.laryngeal web
ans-a
 10.Multiple nasal polypi in children should guide the clinician to search for underlying
 a.Mucoviscidosis
 b.Celiac disease
 c.Hirschsprung disease
 d.Sturge Weber syndrome
ans-a

 Cystic fibrosis (also known as CF or mucoviscidosis) is an autosomal genetic disease affecting most critically the lungs, and also the pancreas, liver, and intestine. It is characterized by abnormal transport of chloride and sodium across epithelium, leading to thick, viscous secretions..... Mucus in the paranasal sinuses is equally thick and may also cause blockage of the sinus passages, leading to infection. This may cause facial pain, fever, nasal drainage, and headaches. Individuals with CF may develop overgrowth of the nasal tissue (nasal polyps) due to inflammation from chronic sinus infections. Recurrent sinonasal polyps can occur in as many as 10% to 25% of CF patients. These polyps can block the nasal passages and increase breathing difficulties...............

APPG 2012 - OPTHALMOLOGY MCQS

APPG 2012  - OPTHALMOLOGY MCQS
 1.Cyclitic membrane gives rise to
 a.Exudative retinal detachment
 b.Rhegmatogenosu retinal detachment
 c.Solid retinal detachment
 d.Tractional retinal detachment

ans-d

2.Munsen sign is seen in cases of
 a.Keratoglobus
 b.Buphthalmos
 c.Keratoconus
 d.Anterior staphyloma
ans-c

 3.The following bacterium is capable of invading the normal cornea through an intact epithelium
 a.Staphylococcus aureus
 b.N.gonorrheae
 c.Streptococcus pneumoniae
 d.Pseudomonas
ans-b
4.A single dose treatment with which one of the following antibacterial drugs is effective in trachoma
 a.Sulphonamide
 b.Erythromycin
 c.Doxycycline
 d.Azithromycin
ans d


 5.Band shaped keratopathy is treated with
 a.Propamidine isethionate
 b.EDTA (Ethylenediamine tetra acetic acid)
 c.Polyhexamethyl biguanide
 d.Chlorhexidine
and-b


 6.Exposure keratopathy is seen in cases of paralysis of
 a.Oculomotor nerve
 b.Trigeminal nerve
 c.Abducens nerve
 d.Facial nerve

ans-d
 7.One of the following is tried to prevent recurrence of pterygium after removal
 a.Mitomycin drops
 b.Chloromycetin
 c.Natamycin
 d.Amphotericin B

ans-a
 8.Photophthalmia is caused by
 a.Infra red rays
 b.Ultra voilet rays
 c.X rays
 d.Beta radiation
ans b

 9.Wernicke hemianopic pupillary response is seen with a lesion at the
 a.Optic chiasma
 b.Optic tract
 c.Lateral geniculate body
 d.Optic radiation

ans-B
 10.One of the following is not true for the ciliary body
 a.Extends just 10mm from the corneoscleral junction
 b.Produces aqueous humor
 c.Is responsible for accomodation 
 d.Consists of the pars plicata and pars plana

ans-a

Drugs and Adverse effects

Drugs and Adverse effects

Drugs specific adverse effect :::

ü Vanishing bile duct syndome -- chlorpromazine

ü Coronary steal phenomena -- dipyridamole and isoflurane

ü Toxic ambylopia --- ethambutol

ü Fatal myocarditis ---clozapine

ü Idiosyncratic hepatic necrosis in infant --sodium valproate

ü Pseudo porphyria -- piroxicam

ü Amotivational syndrome-- marijuana

ü Fetal aplasia cutis -- carbimazole/methimazole in pregnancy

ü Drug induced mysthenia gravis-- d- penicilamine

ü Salt and pepper fundus -- thioridazine

ü Blue halo effect -- sidenafil

ü Calciphylaxis -- warfarin use in hemodylasis pt

ü Livedo reticularis -- amantidine

ü DRESS ie drug related eosinophila and systemic symptoms -- allopurinol

ü Pseudolymphoma syndrome -- anticonvulsants

ü Delayed bone marrow suppresion --nitrosourea anticancer drugs

ü Predisposition to listeria infection -- fludarabine

ü FSGS --heroin

ü Peripheral neuropathy resembling motor neuron disease -- dapsone

ü Vacuolar myopathy -- vincristine

ü Acute hepatic necrosis in pregnancy -- tetracycline

ü Cytokine release syndrome --muromonab cd3

ü Hand foot syndrome -- capcitabine

ü Hemorragic cystitis -- ifosfamide


ü  Haemolytic uremic syndrome -- mitomycine c

Friday, 3 January 2014

WORLD Health Day

WORLD Health Day
 WORLD Health Day, which is celebrated every 7th of April since 1948 marks the founding anniversary of the World Health Organization.
 Every year, a theme is selected to highlight a priority area of worldwide public health concern.

 The 2013 World Health Day theme is controlling BLOOD PRESSURE

world Cancer statistics

world  Cancer statistics
Most Common Cancer In Men :
 1.Prostate
 2.Lung
 3.Colorectal
 Most Common Cancer In Women :
 1.Breast
 2.Lung
 3.Colorectal
 Gynecologic Cancer :
 1.Endometrium
 2.Ovarian
 3.Cervical ( Least common due to cervical Pap smear detecting dysplasia)
 Most Common Cancer In Children :
 Acute lymphoblastic leukemia
 Most Common Cause Of Cancer Related Death In Men:
 1.Lung
 2.Prostate
 3.Colorectal
 Most Common Cause Of Cancer Related Death In Women :
 1.Lung
 2.Breast

 3.Colorectal

ALCOHAL DEPENDENCE-DRUGS ARE USED

DRUGS ARE USED IN REHABILITATION OF ALCOHAL DEPENDENCE PATIENTS :


SEE MNEMONIC= ''Say No To DARO''
 Say - SSRIs
 No - naltrexone,nalmefene
 To - topiramate
 D - disulfiram
 A - acamprosate
 R - ramonibant (its a cannabinol receptor antagonist)

 O - ondansetron